Relative risk rather than absolute risk reduction should be preferred to sensitise the public to preventive actions
نویسندگان
چکیده
منابع مشابه
Should treatment recommendations for lipid lowering drugs be based on absolute coronary risk or risk reduction?
When individual variables were subjected to logistic regression, male sex, age, blood pressure, smoking status, and cholesterol concentrations were all significant predictors of heart disease but when corrected for the Framingham risk score no single factor remained predictive on its own. The figure shows the number of coronary events predicted by the Framingham model and the number observed du...
متن کاملMeasuring the Size of a Treatment Effect: Relative Risk Reduction, Absolute Risk Reduction, and Number Needed to Treat
Hussein Hollands, MD, MS (epid) Peter J. Kertes, MD, CM, FRCS(C) The purpose of this review article is to outline a few concepts that are useful for interpreting the results of a randomized clinical trial (RCT). Specifically, we will focus on measures of the size of a treatment effect— relative risk ratio (RRR), absolute risk ratio, and number needed to treat (NNT). These concepts are important...
متن کاملTips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat.
Physicians, patients and policy-makers are influenced not only by the results of studies but also by how authors present the results. Depending on which measures of effect authors choose, the impact of an intervention may appear very large or quite small, even though the underlying data are the same. In this article we present 3 measures of effect — relative risk reduction, absolute risk reduct...
متن کاملShould the first-trimester aneuploidy screen be maternal age adjusted? Screening by absolute risk versus risk adjusted to maternal age.
OBJECTIVE To compare the absolute risk (AR) screening approach to the current approach of risk adjusted to maternal age in patients undergoing first-trimester screening (FTS). MATERIAL AND METHODS Three-stage retrospective analysis of 3073 pregnancies that had FTS during 2006-2007. (1) Distribution analysis of AR as defined by (final FTS risk)/(risk by age). (2) Analysis of the screen-positiv...
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Downloa 3. Andreou I, Tousoulis D, Miliou A, et al. Effects of rosuvastatin on myeloperoxidase levels in patients with chronic heart failure: a randomized placebo-controlled study. Atherosclerosis 2010;210:194–8. 4. Tousoulis D, Andreou I, Tsiatas M, et al. Effects of rosuvastatin and allopurinol on circulating endothelial progenitor cells in patients with congestive heart failure: the impact o...
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ژورنال
عنوان ژورنال: Gut
سال: 2021
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2021-324689